ReconMap: an interactive visualization of human metabolism

Bioinformatics. 2017 Feb 15;33(4):605-607. doi: 10.1093/bioinformatics/btw667.

Abstract

Motivation: A genome-scale reconstruction of human metabolism, Recon 2, is available but no interface exists to interactively visualize its content integrated with omics data and simulation results.

Results: We manually drew a comprehensive map, ReconMap 2.0, that is consistent with the content of Recon 2. We present it within a web interface that allows content query, visualization of custom datasets and submission of feedback to manual curators.

Availability and implementation: ReconMap can be accessed via http://vmh.uni.lu , with network export in a Systems Biology Graphical Notation compliant format released under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. A Constraint-Based Reconstruction and Analysis (COBRA) Toolbox extension to interact with ReconMap is available via https://github.com/opencobra/cobratoolbox .

Contact: ronan.mt.fleming@gmail.com.

MeSH terms

  • Databases, Factual
  • Genome, Human*
  • Humans
  • Metabolic Networks and Pathways*
  • Software*
  • Systems Biology / methods*