Predictors of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People Living with HIV Infection in St. Petersburg, Russia

AIDS Behav. 2018 Mar;22(3):791-799. doi: 10.1007/s10461-016-1638-9.

Abstract

Over 1 million HIV infections have been diagnosed in Russia, and HIV care uptake and viral suppression are very low. 241 HIV-positive individuals in St. Petersburg were enrolled through social networks, provided blood for viral load testing, and completed measures of medication-taking adherence, readiness, and self-efficacy; psychosocial well-being; and substance use. Outcomes included attending an HIV care appointment in the past 6 months, >90% ART adherence, and undetectable viral load. 26% of participants had no recent care appointment, 18% had suboptimal adherence, and 56% had detectable viral load. Alcohol use consistently predicted all adverse health outcomes. Having no recent care visit was additionally associated with being single and greater past-month drug injection frequency. Poor adherence was additionally predicted by lower medication-taking self-efficacy and lower anxiety. Detectable viral load was additionally related to younger age. Comprehensive interventions to improve HIV care in Russia must address substance abuse, anxiety, and medication-taking self-efficacy.

Keywords: HIV care linkage and retention; HIV medical care; HIV services; HIV-positive; Persons living with HIV; Russia.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Retroviral Agents / therapeutic use*
  • Anxiety / complications*
  • Anxiety / psychology
  • Continuity of Patient Care*
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • HIV Infections / psychology
  • Humans
  • Male
  • Medication Adherence*
  • Middle Aged
  • Retention in Care*
  • Risk-Taking
  • Russia / epidemiology
  • Self Efficacy
  • Substance-Related Disorders / complications*
  • Substance-Related Disorders / psychology
  • Viral Load / drug effects*

Substances

  • Anti-Retroviral Agents