Effects of ethyl chloride spray on early recovery after total knee arthroplasty: A prospective study

J Orthop Sci. 2017 Jan;22(1):89-93. doi: 10.1016/j.jos.2016.10.005. Epub 2016 Dec 13.

Abstract

Background: Ethyl chloride spray as a common cooling modality has been widely used in acute sports injuries and joint injection procedures. Several clinical studies reported that use of ethyl chloride has positive effects on swelling, pain reduction and recovery from sports injuries. The main aim of present study was to analyze whether postoperative use of ethyl chloride spray benefits results after primary total knee arthroplasty (TKA).

Methods: Between April 1, 2014 and October 21, 2015, 306 subjects undergoing primary TKA used ethyl chloride spray for improving recovery from the damage from surgery. After exclusion of 31 subjects due to adverse events including periprosthetic joint infection (PJI), deep venous thrombosis (DVT), acute myocardial infarction, finally 275 subjects' data regarding pain score, knee range of motion (ROM), knee girth, time of being able to reach 90° knee flexion and analgesic consumption were analyzed.

Results: Significant differences in pain score, knee ROM at each time point and knee girth at on 21st and 28th postoperatively were detected without increased incidence of adverse events. Besides, time of being able to reach 90° knee flexion and analgesic consumption in the treatment group were significantly decreased in comparison to the control group.

Conclusion: Use of ethyl chloride spray can help patients recovery from the damage from TKA safely.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Aged
  • Arthroplasty, Replacement, Knee / adverse effects
  • Arthroplasty, Replacement, Knee / methods*
  • China
  • Ethyl Chloride / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Osteoarthritis, Knee / surgery
  • Pain Measurement / drug effects*
  • Pain, Postoperative / drug therapy*
  • Pain, Postoperative / physiopathology
  • Patient Satisfaction / statistics & numerical data
  • Prospective Studies
  • Range of Motion, Articular / drug effects*
  • Range of Motion, Articular / physiology
  • Reference Values
  • Single-Blind Method
  • Treatment Outcome

Substances

  • Ethyl Chloride