Host-Associated Absence of Human Puumala Virus Infections in Northern and Eastern Germany

Emerg Infect Dis. 2017 Jan;23(1):83-86. doi: 10.3201/eid2301.160224.

Abstract

Human hantavirus disease cases, caused by Puumala virus (PUUV), are mainly recorded in western and southern areas of Germany. This bank vole reservoir survey confirmed PUUV presence in these regions but its absence in northern and eastern regions. PUUV occurrence is associated with the presence of the Western bank vole phylogroup.

Keywords: Central Europe; Germany; Puumala virus; bank vole; cytochrome b; endemic region; evolutionary lineage; nephropathia epidemica; outbreak; phylogroup; viruses; zoonoses.

MeSH terms

  • Animals
  • Antibodies, Viral / blood*
  • Arvicolinae / classification
  • Arvicolinae / genetics
  • Arvicolinae / virology*
  • Cytochromes b / genetics
  • Disease Reservoirs / veterinary*
  • Disease Reservoirs / virology
  • Epidemiological Monitoring / veterinary
  • Genetic Predisposition to Disease
  • Genotyping Techniques
  • Germany / epidemiology
  • Hantavirus Infections / epidemiology*
  • Hantavirus Infections / genetics
  • Hantavirus Infections / veterinary*
  • Hantavirus Infections / virology
  • Humans
  • Phylogeny*
  • Phylogeography
  • Puumala virus / pathogenicity
  • Puumala virus / physiology

Substances

  • Antibodies, Viral
  • Cytochromes b