Polymorphic eruption of pregnancy: Review of literature

J Obstet Gynaecol. 2017 Feb;37(2):137-140. doi: 10.1080/01443615.2016.1225019. Epub 2016 Dec 14.

Abstract

Polymorphic Eruption of Pregnancy (PEP) is one of the most common dermatosis related to pregnancy. PEP usually consists of pruritic papules and plaques appearing in the third trimester of pregnancy. It is more common in primigravidae and twin pregnancies. Although not associated with poorer foetal or maternal outcomes, it may be hard for pregnant women to endure. The diagnosis is easy if suspected, though sometimes it may be hard to distinguish from other dermatosis such as atopic eczema of pregnancy, pemphigoid gestationis or dermatitis. Topical treatment with emollients and low-medium potency steroids is usually effective but systemic steroid treatment may be required. PEP is self-limiting and resolves days or weeks after the first appearance or after delivery. In this article, the authors aim to review the literature published from 2000 onwards regarding the subject, either in English or Portuguese.

Keywords: PEP; PUPPP; dermatosis of pregnancy; polymorphic eruption of pregnancy; pruritic urticarial papules and plaques of pregnancy.

Publication types

  • Review

MeSH terms

  • Administration, Topical
  • Adrenal Cortex Hormones / therapeutic use*
  • Dermatologic Agents / administration & dosage*
  • Diagnosis, Differential
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Pregnancy Complications / drug therapy*
  • Pregnancy Trimester, Third
  • Pruritus / diagnosis*
  • Pruritus / drug therapy*
  • Risk Factors

Substances

  • Adrenal Cortex Hormones
  • Dermatologic Agents

Supplementary concepts

  • Pruritic urticarial papules plaques of pregnancy