The treatment of hidradenitis suppurativa with the glucagon-like peptide-1 agonist liraglutide

Br J Dermatol. 2017 Sep;177(3):858-859. doi: 10.1111/bjd.15233. Epub 2017 Jul 14.

Abstract

Hidradenitis suppurativa (HS) is a cutaneous disease associated with systemic inflammation, obesity and metabolic syndrome. Effective treatment options are limited. The antidiabetic agents, incretins, have been used successfully to treat psoriasis - a disease also associated with metabolic syndrome. We report the use of liraglutide, a glucagon-like peptide-1 agonist, in a patient with HS, leading to subsequent weight loss and improvement in disease control. To our knowledge, this is the first report of liraglutide used in the treatment of HS.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Hidradenitis Suppurativa / drug therapy*
  • Humans
  • Hypoglycemic Agents / therapeutic use*
  • Liraglutide / therapeutic use*
  • Treatment Outcome
  • Weight Loss / drug effects

Substances

  • Hypoglycemic Agents
  • Liraglutide