Genetic polymorphisms of 17 Y-chromosomal STRs in the Chengdu Han population of China

Hui Wang; Jiong Mao; Yu Xia; Xiaogang Bai; Wenqing Zhu; Duo Peng; Weibo Liang

doi:10.1007/s00414-016-1511-4

Genetic polymorphisms of 17 Y-chromosomal STRs in the Chengdu Han population of China

Int J Legal Med. 2017 Jul;131(4):967-968. doi: 10.1007/s00414-016-1511-4. Epub 2016 Dec 12.

Authors

Hui Wang¹, Jiong Mao¹, Yu Xia¹, Xiaogang Bai¹, Wenqing Zhu², Duo Peng³, Weibo Liang⁴

Affiliations

¹ Department of Forensic Genetics, Institute of Forensic Science, Chengdu Public Security Bureau, Chengdu, Sichuan, 610081, China.
² Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, China.
³ Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, China. pengduo.pengduo@qq.com.
⁴ Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, China. liangweibo@gmail.com.

PMID: 27942858
DOI: 10.1007/s00414-016-1511-4

Abstract

Chengdu is located at the center of Sichuan Province in southwestern China, and its primary demographic group is the Han population. The aim of this study was to contribute data detailing 17 Y-short tandem repeat (Y-STR) loci from 3291 Chengdu Han male samples analyzed with the AmpFLSTR^® Yfiler^® PCR Amplification Kit. We observed 2228 different haplotypes, and haplotype diversity (HD) was 0.9992. Gene diversity (GD) values for the 17 Y-STR loci of the Chengdu Han population ranged from 0.4156 to 0.9529. Haplotype match probability (HMC) was 0.0011. Compared with 13 reference populations of six provinces surrounding Chengdu, we observed that the Chengdu Han population was significantly different from each of these populations.

Keywords: Chengdu Han population; Haplotypes; Y-STRs; Yfiler®.

MeSH terms

China
Chromosomes, Human, Y*
DNA Fingerprinting
Ethnicity / genetics*
Genetics, Population*
Haplotypes
Humans
Male
Microsatellite Repeats*
Polymerase Chain Reaction / instrumentation
Polymorphism, Genetic*