New oral anticoagulants in patients with chronic kidney disease

Nefrologia. 2017 May-Jun;37(3):244-252. doi: 10.1016/j.nefro.2016.08.006. Epub 2016 Dec 9.
[Article in English, Spanish]

Abstract

Patients with chronic kidney disease (CKD) develop bleeding and thrombotic tendencies, so the indication of anticoagulation at the onset of atrial fibrillation (AF) is complex. AF is the most common chronic cardiac arrhythmia, and thromboembolism and ischemic stroke in particular are major complications. In recent years, new oral anticoagulant drugs have been developed, and they have shown superiority over the classical AVK in preventing stroke, systemic embolism and bleeding risk, constituting an effective alternative to those resources.

Keywords: Anticoagulantes orales; Atrial fibrillation; Chronic kidney disease; Enfermedad renal crónica; Fibrilación auricular; Oral anticoagulants.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Anticoagulants / administration & dosage*
  • Atrial Fibrillation / complications*
  • Humans
  • Renal Insufficiency, Chronic / complications*
  • Stroke / etiology*
  • Stroke / prevention & control*
  • Thromboembolism / etiology*
  • Thromboembolism / prevention & control*

Substances

  • Anticoagulants