A fluorescein angiographic study on patients with proliferative vitreoretinopathy treated by vitrectomy and intraocular daunomycin

Int Ophthalmol. 1989 May;13(3):211-6. doi: 10.1007/BF02028213.

Abstract

Fluorescein angiographic findings in patients with proliferative vitreoretinopathy treated by victrectomy, silicone oil tamponade and intraocular daunomycin are compared to findings in patients who received the same treatment but no intraocular drug. A difference between drug treated and untreated eyes was not discovered. We observed, however, a delayed arteriovenous passage time, cystoid macular edema, ectopia of the foveolar region and late hyperfluorescence of the optic disk; these findings might partly explain the visual results. Reduction of redetachment and thus prevention of reoperations by treatment with antiproliferative drugs may decrease the rate of cystoid macular edema and thus improve the functional results of surgical treatment.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Choroid / pathology*
  • Daunorubicin / therapeutic use*
  • Female
  • Fluorescein Angiography*
  • Humans
  • Macular Edema / complications
  • Male
  • Middle Aged
  • Photography
  • Pigment Epithelium of Eye / pathology
  • Retinal Diseases / therapy*
  • Silicone Oils
  • Uveal Diseases / complications
  • Visual Acuity
  • Vitrectomy*

Substances

  • Silicone Oils
  • Daunorubicin