Short-Term Outcomes of 100 Consecutive Kidney Transplantations in a 3-Year Period: A Single-Center Experience

Transplant Proc. 2016 Nov;48(9):2906-2909. doi: 10.1016/j.transproceed.2016.09.017.

Abstract

Background: The results of kidney transplantation have improved significantly in the last decade with patient and graft survival rates that range from 92% to 95%.

Methods: We analyzed the clinical results in the last 100 consecutive patients with a follow-up of 6-42 months at our institution. We also made a general evaluation of the patients before surgery as candidates for transplantation and divided them into 3 groups (good, moderate, and poor).

Results: We had 8 living donors and 92 cadaveric kidney transplantation cases. Principal cause of donor death was cerebrovascular disease accounting for 64%. Mean age of recipients was 55.1 ± 12.9 years with a total of 65 males. Currently there are 96 functioning allografts. During this 3-year period, 2 patients suffered graft loss and 2 patients died with a functioning allograft. We studied whether there were statistically significant differences in renal function (Modification of Diet in Renal Disease Study Equation [MDRD]) at 12 months and at last visit with respect to the evaluation of recipient as candidate for renal transplantation.

Conclusion: Our observations suggest great improvement of early results of renal transplantation in recent years, including complex cases. In this 3-year period we had a patient survival rate of 98% and a graft survival rate of 96% of cases. Further dedicated prospective studies that aim to evaluate or to propose possible recipient-related predictors for kidney transplantation outcomes in different populations are needed.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Aged
  • Allografts / physiology*
  • Epidemiologic Methods
  • Female
  • Glomerular Filtration Rate / physiology
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kidney Transplantation / methods
  • Kidney Transplantation / mortality*
  • Living Donors / statistics & numerical data
  • Male
  • Middle Aged
  • Renal Insufficiency, Chronic / mortality
  • Renal Insufficiency, Chronic / physiopathology
  • Renal Insufficiency, Chronic / surgery
  • Time Factors
  • Tissue Donors / statistics & numerical data
  • Transplantation, Homologous / methods
  • Transplantation, Homologous / mortality

Substances

  • Immunosuppressive Agents