Decoding the Ecological Function of Accessory Genome

Michelle Qiu Carter

doi:10.1016/j.tim.2016.11.012

Decoding the Ecological Function of Accessory Genome

Trends Microbiol. 2017 Jan;25(1):6-8. doi: 10.1016/j.tim.2016.11.012. Epub 2016 Dec 2.

Author

Michelle Qiu Carter¹

Affiliation

¹ US Department of Agriculture, Agricultural Research Service, Western Regional Research Center, Produce Safety and Microbiology Research Unit, Albany, CA, USA. Electronic address: michelle.carter@ars.usda.gov.

PMID: 27919552
DOI: 10.1016/j.tim.2016.11.012

Abstract

Shiga toxin-producing Escherichia coli O157:H7 primarily resides in cattle asymptomatically, and can be transmitted to humans through food. A study by Lupolova et al. applied a machine-learning approach to complex pan-genome information and predicted that only a small subset of bovine isolates have the potential to cause diseases in humans.

Keywords: Shiga toxin-producing Escherichia coli; accessory genome; enterohemorrhagic Escherichia coli; pan-genome; support vector machine; zoonotic potential.

Publication types

Comment

MeSH terms

Animals
Cattle
Escherichia coli Infections / microbiology
Escherichia coli Infections / transmission*
Escherichia coli O157 / genetics*
Escherichia coli O157 / isolation & purification
Escherichia coli O157 / metabolism
Escherichia coli O157 / pathogenicity*
Escherichia coli Proteins / genetics*
Food Microbiology
Genome, Bacterial / genetics
Genomic Islands / genetics
Humans
Phosphoproteins / genetics*
Shiga Toxin / metabolism*
Virulence Factors / genetics

Substances

Escherichia coli Proteins
LEE protein, E coli
Phosphoproteins
Virulence Factors
Shiga Toxin