Carbon Nanodots as Peroxidase Nanozymes for Biosensing

Molecules. 2016 Dec 2;21(12):1653. doi: 10.3390/molecules21121653.

Abstract

'Nanozymes', a term coined by Scrimin, Pasquato, and co-workers to describe nanomaterials with enzyme-like characteristics, represent an exciting and emerging research area in the field of artificial enzymes. Indubitably, the last decade has witnessed substantial advancements in the design of a variety of functional nanoscale materials, including metal oxides and carbon-based nanomaterials, which mimic the structures and functions of naturally occurring enzymes. Among these, carbon nanodots (C-dots) or carbon quantum dots (CQDs) offer huge potential due to their unique properties as compared to natural enzymes and/or classical artificial enzymes. In this mini review, we discuss the peroxidase-like catalytic activities of C-dots and their applications in biosensing. The scope intends to cover not only the C-dots but also graphene quantum dots (GQDs), doped C-dots/GQDs, carbon nitride dots, and C-dots/GQDs nanocomposites. Nevertheless, this mini review is designed to be illustrative, not comprehensive.

Keywords: biosensors; carbon nanodots; carbon nitride dots; carbon quantum dots; enzyme mimetics; graphene quantum dots; peroxidases; photoluminescence; tetramethylbenzidine.

Publication types

  • Review

MeSH terms

  • Biomimetic Materials / chemistry*
  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods*
  • Carbon / chemistry*
  • Graphite / chemistry
  • Nanocomposites / chemistry*
  • Peroxidase / chemistry
  • Quantum Dots / chemistry*

Substances

  • Carbon
  • Graphite
  • Peroxidase