Abstract
We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam by 73%. During the shortage period, hospital mortality decreased (P=.03), while hospital length of stay remained unchanged. Infect Control Hosp Epidemiol 2017;38:356-359.
MeSH terms
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Academic Medical Centers
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Anti-Bacterial Agents / economics*
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Anti-Bacterial Agents / supply & distribution*
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Antimicrobial Stewardship*
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Hospital Mortality / trends*
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Humans
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Length of Stay / statistics & numerical data*
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Linear Models
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Meropenem
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Missouri
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Penicillanic Acid / analogs & derivatives
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Penicillanic Acid / supply & distribution
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Piperacillin / supply & distribution
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Piperacillin, Tazobactam Drug Combination
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Retrospective Studies
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Thienamycins / supply & distribution
Substances
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Anti-Bacterial Agents
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Thienamycins
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Piperacillin, Tazobactam Drug Combination
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Penicillanic Acid
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Meropenem
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Piperacillin