Recent perspectives of stem cell use in cardiac disorders

Hellenic J Cardiol. 2017 Mar-Apr;58(2):105-109. doi: 10.1016/j.hjc.2016.11.031. Epub 2016 Dec 2.

Abstract

Stem cells and progenitor cells have unique abilities for self-renewal. These cells have the differentiation capacity to develop as various types of cells, including cardiac cells. Because atherosclerosis is considered a disease of endothelial dysfunction, regenerative cell-based therapy is an effective approach to ameliorate atherosclerotic pathogenesis. Recent studies are now focused on the effective targeting of stem cells to the site of interest. The echogenic liposome approach has good potential for efficiently delivering drugs as well as the ability to reduce atheroma progression. The present review article enhances recent perspectives on the stem cell approach, including new delivery approaches for cardiac disorders.

Keywords: Atherosclerosis; Cardiac disorders; Liposomes; Stem cells.

Publication types

  • Review