CHROMagar mSuperCARBA performance in carbapenem-resistant Enterobacteriaceae isolates characterized at molecular level and routine surveillance rectal swab specimens

Diagn Microbiol Infect Dis. 2017 Mar;87(3):207-209. doi: 10.1016/j.diagmicrobio.2016.11.014. Epub 2016 Nov 25.

Abstract

Performance of the CHROMagar mSuperCARBA media was assessed in both well-characterized carbapenem-resistant Enterobacteriaceae (n=52) and routine surveillance rectal swab specimens (n=211). Limit of detection ranged between 101 and 102CFU/mL except for OXA-48 producers with low-carbapenem MICs (106CFU/mL). High sensitivity (100%) and specificity (100%) were obtained with rectal swabs.

Keywords: Carbapenemase; Chromogenic media; Clinical; Detection; Enterobacteriaceae.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacteriological Techniques
  • Carbapenems / pharmacology*
  • Chromogenic Compounds
  • Culture Media
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / diagnosis*
  • Enterobacteriaceae Infections / drug therapy
  • Humans
  • Limit of Detection
  • Microbial Sensitivity Tests
  • Rectum / microbiology
  • Sensitivity and Specificity
  • beta-Lactam Resistance / physiology*

Substances

  • Anti-Bacterial Agents
  • Carbapenems
  • Chromogenic Compounds
  • Culture Media