Abstract
Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive form of corneal dystrophy characterised by subepithelial and stromal amyloid deposits. It is relatively common in Japan. It usually presents in the first two decades of life with subepithelial nodular lesions that later coalesce to form mulberry-like opacities. Although various surgical modalities have been attempted, recurrence remains a major challenge.
Keywords:
Cornea; Dystrophy.
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MeSH terms
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Amyloidosis, Familial* / diagnosis
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Amyloidosis, Familial* / genetics
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Amyloidosis, Familial* / physiopathology
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Amyloidosis, Familial* / therapy
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Antigens, Neoplasm / genetics
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Cell Adhesion Molecules / genetics
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Corneal Dystrophies, Hereditary* / diagnosis
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Corneal Dystrophies, Hereditary* / genetics
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Corneal Dystrophies, Hereditary* / physiopathology
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Corneal Dystrophies, Hereditary* / therapy
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Diagnosis, Differential
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Genetic Predisposition to Disease
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Humans
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Mutation
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Ophthalmologic Surgical Procedures
Substances
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Antigens, Neoplasm
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Cell Adhesion Molecules
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TACSTD2 protein, human
Supplementary concepts
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Corneal dystrophy, gelatinous drop-like