An attenuated calcium signaling and pre-emptive activation of UPR pathway together contribute to ER and calcium stress resilience of Lepidopteran insect cells

Biochim Biophys Acta Gen Subj. 2017 Mar;1861(3):504-521. doi: 10.1016/j.bbagen.2016.11.035. Epub 2016 Nov 28.

Authors

Ayushi Guleria¹, Vijaypal Singh¹, Sudhir Chandna²

Affiliations

¹ Division of Natural Radiation Response Mechanisms, Institute of Nuclear Medicine and Allied Sciences, Delhi 110054, India.
² Division of Natural Radiation Response Mechanisms, Institute of Nuclear Medicine and Allied Sciences, Delhi 110054, India. Electronic address: sudhirchandna@yahoo.com.

PMID: 27908702
DOI: 10.1016/j.bbagen.2016.11.035

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Calcium / metabolism*
Calcium Signaling / physiology*
Cell Line
Endoplasmic Reticulum / metabolism
Endoplasmic Reticulum / physiology*
Endoplasmic Reticulum Stress / physiology*
HEK293 Cells
Humans
Insecta / metabolism
Insecta / physiology*
Lepidoptera / metabolism
Lepidoptera / physiology*
Signal Transduction / physiology
Unfolded Protein Response / physiology*

Substances

Calcium