A DNA element that remembers winter

Nat Genet. 2016 Nov 29;48(12):1451-1452. doi: 10.1038/ng.3727.

Abstract

Polycomb-mediated silencing of the floral repressor gene FLC in response to long-term cold is a central event during vernalization in Arabidopsis thaliana, but how it is initiated is unclear. Two new studies identify a DNA element that mediates FLC silencing by attracting a pair of transcriptional repressors, VAL1 and VAL2, which in turn trigger epigenetic silencing by the Polycomb complex PHD-PRC2.

Publication types

  • Comment

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis Proteins / genetics*
  • DNA
  • Flowers / genetics
  • Gene Expression Regulation, Plant
  • Gene Silencing
  • MADS Domain Proteins / genetics*

Substances

  • Arabidopsis Proteins
  • MADS Domain Proteins
  • DNA