Genome Annotation

Methods Mol Biol. 2017:1525:107-121. doi: 10.1007/978-1-4939-6622-6_5.

Abstract

The dynamic structure and functions of genomes are being revealed simultaneously with the progress of technologies and researches in genomics. Evidence indicating genome regional characteristics (genome annotations in a broad sense) provide the basis for further analyses. Target listing and screening can be effectively performed in silico using such data. Here, we describe steps to obtain publicly available genome annotations or to construct new annotations based on your own analyses, as well as an overview of the types of available genome annotations and corresponding resources.

Keywords: Epigenetic marks; Gene functions; Genome annotation; Genome browser; RNA-Seq.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Genetic
  • Epigenesis, Genetic / genetics*
  • Genomics / methods*
  • Software