Data for increased Rho kinase activity in type 2 diabetic patients

Lei Liu; Lun Tan; Jinsheng Lai; Sheng Li; Dao Wen Wang

doi:10.1016/j.dib.2016.11.032

Data for increased Rho kinase activity in type 2 diabetic patients

Data Brief. 2016 Nov 16:9:978-982. doi: 10.1016/j.dib.2016.11.032. eCollection 2016 Dec.

Authors

Lei Liu¹, Lun Tan¹, Jinsheng Lai¹, Sheng Li¹, Dao Wen Wang¹

Affiliation

¹ Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Abstract

The data presented in this article are related to the research article entitled "Enhanced Rho-Kinase Activity: Pathophysiological Relevance in Type 2 Diabetes" [1]. Rho-Kinase has attracted a great deal of interest as a novel therapeutic target in cardiovascular diseases. These data describe the observed relationship of Rho-Kinase activity with type 2 diabetic patients. Rho-Kinase activity is determined by immunoblotting of peripheral blood leukocytes with the Phospho-Thr853 in the myosin-binding subunit of myosin light-chain phosphatase. The level of IL-6 is measured using Enzyme-linked immunosorbent assay.