Medicinal uses, chemistry and pharmacology of Dillenia species (Dilleniaceae)

Phytochemistry. 2017 Feb:134:6-25. doi: 10.1016/j.phytochem.2016.11.010. Epub 2016 Nov 23.

Abstract

The genus Dillenia is comprised of about 100 species of evergreen and deciduous trees or shrubs of disjunct distribution in the seasonal tropics of Madagascar through South and South East Asia, Malaysia, North Australia, and Fiji. Species from this genus have been widely used in medicinal folklore to treat cancers, wounds, jaundice, fever, cough, diabetes mellitus, and diarrhea as well as hair tonics. The plants of the genus also produce edible fruits and are cultivated as ornamental plants. Flavonoids, triterpenoids, and miscellaneous compounds have been identified in the genus. Their extracts and pure compounds have been reported for their antimicrobial, anti-inflammatory, cytotoxic, antidiabetes, antioxidant, antidiarrheal, and antiprotozoal activities. Mucilage from their fruits is used in drug formulations.

Keywords: Dillenia; Dilleniaceae; Medicinal uses; Pharmacology; Phytochemical.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use
  • Antioxidants / therapeutic use
  • Australia
  • Dilleniaceae / chemistry*
  • Fiji
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Flavonoids / therapeutic use
  • Madagascar
  • Malaysia
  • Plant Extracts / chemistry
  • Plants, Medicinal / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification
  • Triterpenes / therapeutic use

Substances

  • Anti-Infective Agents
  • Antioxidants
  • Flavonoids
  • Plant Extracts
  • Triterpenes