Association of STAT5A Gene Variants with Milk Production Traits in Agerolese Cattle

Maria Selvaggi; Sara Albarella; Cataldo Dario; Vincenzo Peretti; Francesca Ciotola

doi:10.1007/s10528-016-9781-6

Association of STAT5A Gene Variants with Milk Production Traits in Agerolese Cattle

Biochem Genet. 2017 Apr;55(2):158-167. doi: 10.1007/s10528-016-9781-6. Epub 2016 Nov 24.

Authors

Maria Selvaggi¹, Sara Albarella², Cataldo Dario³, Vincenzo Peretti², Francesca Ciotola²

Affiliations

¹ Section of Veterinary Science and Animal Production, Department of DETO, University of Bari 'Aldo Moro', strada prov.le per Casamassima km 3, 70010, Valenzano, BA, Italy. maria.selvaggi@uniba.it.
² Department of Veterinary Medicine and Animal Production, University Federico II, 80137, Naples, Italy.
³ Section of Veterinary Science and Animal Production, Department of DETO, University of Bari 'Aldo Moro', strada prov.le per Casamassima km 3, 70010, Valenzano, BA, Italy.

PMID: 27885437
DOI: 10.1007/s10528-016-9781-6

Abstract

Two polymorphisms at STAT5A gene were investigated in a sample of Agerolese cows. The aims of the present study were to estimate the allele and genotype frequencies and to investigate the relationship among genotypes and milk production traits. Milk production traits were analyzed for each animal in the first, second, third, and fourth lactation. No genetic variability was found at STAT5A/AvaI locus. At STAT5A/MslI locus, the frequencies of T and C alleles were 0.875 and 0.125, respectively. Significant differences between genotypes were found: TT cow produced a milk with a higher content of fat and protein when compared with TC.

Keywords: Agerolese cattle breed; Gene polymorphisms; Milk quality; Milk yield; STAT5A.

MeSH terms

Alleles*
Animals
Cattle / genetics*
Female
Genetic Variation*
Milk*
Quantitative Trait, Heritable*
STAT5 Transcription Factor / genetics*

Substances

STAT5 Transcription Factor