Treatment options for methicillin-resistant Staphylococcus aureus (MRSA) infection: Where are we now?

B Edwards; R Andini; S Esposito; P Grossi; D Lew; T Mazzei; A Novelli; A Soriano; I M Gould

doi:10.1016/j.jgar.2014.03.009

Treatment options for methicillin-resistant Staphylococcus aureus (MRSA) infection: Where are we now?

J Glob Antimicrob Resist. 2014 Sep;2(3):133-140. doi: 10.1016/j.jgar.2014.03.009. Epub 2014 May 29.

Authors

B Edwards¹, R Andini², S Esposito³, P Grossi⁴, D Lew⁵, T Mazzei⁶, A Novelli⁶, A Soriano⁷, I M Gould⁸

Affiliations

¹ Medical Microbiology Department, Royal Infirmary of Edinburgh, 51 Little France Crescent, Dalkeith Road, Edinburgh EH16 4SA, UK. Electronic address: bex.edwards@gmail.com.
² Second University of Naples, UOC Transplant and Infectious Disease Medicine, AORN Monaldi, Naples, Italy.
³ Department of Medicine, University of Salerno, Salerno, Italy.
⁴ Department of Surgical and Morphological Studies, University of Unisubria, Varese, Italy.
⁵ Chief Infectious Diseases Division, Chief Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva, Switzerland.
⁶ Department of Health Sciences, Clinical Pharmacology and Oncology Section, University of Firenze, Firenze, Italy.
⁷ Department of Infectious Diseases, IDIBAPS, Hospital Clinic of Barcelona, Spain.
⁸ Medical Microbiology Department, Aberdeen Royal Infirmary, Aberdeen, UK.

PMID: 27873719
DOI: 10.1016/j.jgar.2014.03.009

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infection continues to be a substantial global problem with significant associated morbidity and mortality. This review summarises the discussions that took place at the 4th MRSA Consensus Conference in relation to the current treatment options for serious MRSA infections and how to optimise whichever therapy is embarked upon. It highlights the many challenges faced by both the laboratory and clinicians in the diagnosis and treatment of MRSA infections.

Keywords: MRSA; Susceptibility testing; Treatment.

Publication types

Review