The MarginProbe® System: An Innovative Approach to Reduce the Incidence of Positive Margins Found After Lumpectomy

Clin J Oncol Nurs. 2016 Dec 1;20(6):598-599. doi: 10.1188/16.CJON.598-599.

Abstract

The goal of lumpectomy surgery for breast cancer is to completely remove the tumor and have clear margins, reducing the rates of local recurrence. The MarginProbe® System is a new device that can detect microscopic tumor cells at or close to the margin of the surgical resection intraoperatively, providing the surgeon with the ability to re-excise tissue at the time of surgery, reducing the need for a second surgery to obtain clear margins. .

Keywords: MarginProbe® System; breast cancer; lumpectomy; tumor margins.

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Equipment Design
  • Female
  • Follow-Up Studies
  • Humans
  • Intraoperative Care / methods
  • Margins of Excision*
  • Mastectomy, Segmental / instrumentation*
  • Mastectomy, Segmental / methods
  • Middle Aged
  • Neoplasm Invasiveness / pathology
  • Neoplasm Recurrence, Local / prevention & control*
  • Neoplasm, Residual / prevention & control
  • Randomized Controlled Trials as Topic
  • Treatment Outcome
  • United States
  • United States Food and Drug Administration