The Fhit protein: an opportunity to overcome chemoresistance

Aging (Albany NY). 2016 Nov 12;8(11):3147-3150. doi: 10.18632/aging.101123.

Authors

Eugenio Gaudio^{1

2

3}, Francesco Paduano^{3

4}, Carlo M Croce¹, Francesco Trapasso³

Affiliations

¹ Department of Molecular Immunology, Virology and Medical Genetics, The Ohio State University, Columbus, OH, USA.
² Lymphoma & Genomics Research Program, IOR Institute of Oncology Research, Bellinzona, Switzerland.
³ Dipartimento di Medicina Sperimentale e Clinica, University , Catanzaro, Italy.
⁴ Tecnologica Research Institute, Biomedical Section, Crotone, Italy.

No abstract available

Keywords: Fragile Histidine Triad (FHIT); mimetic peptides; reactive oxygen species; targeted therapy; tumor suppressor.

Publication types

Letter

MeSH terms

Acid Anhydride Hydrolases / genetics*
Acid Anhydride Hydrolases / metabolism
Animals
Drug Resistance, Neoplasm / physiology*
Humans
Neoplasm Proteins / genetics*
Neoplasm Proteins / metabolism

Substances

Neoplasm Proteins
fragile histidine triad protein
Acid Anhydride Hydrolases

Grants and funding

R35 CA197706/CA/NCI NIH HHS/United States