Needleless coaxial electrospinning: A novel approach to mass production of coaxial nanofibers

Abstract

Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering.

Keywords: Coaxial electrospinning; Core-shell nanofibers; Fluorescent spectroscopy; Needleless electrospinning.