Screening for oral cancer

J Exp Ther Oncol. 2016 Nov;11(4):303-307.

Abstract

Oral cancer is considered as a serious health problem resulting in high morbidity and mortality. Early detection and prevention play a key role in controlling the burden of oral cancer worldwide. The five-year survival rate of oral cancer still remains low and delayed diagnosis is considered as one of the major reasons. This increases the demand for oral screening. Currently, screening of oral cancer is largely based on visual examination. Various evidence strongly suggest the validity of visual inspection in reducing mortality in patients at risk for oral cancer. Simple visual examination is accompanied with adjunctive techniques for subjective interpretation of dysplastic changes. These include toluidine blue staining, brush biopsy, chemiluminescence and tissue autofluorescence. This review highlights the efficacy of various diagnostic methods in screening of oral cancer.

Keywords: diagnosis; examination; oral cancer; screening.

Publication types

  • Review

MeSH terms

  • Biopsy / methods
  • Delayed Diagnosis
  • Early Detection of Cancer / methods
  • Humans
  • Mass Screening
  • Mouth Neoplasms / diagnosis*
  • Mouth Neoplasms / pathology*
  • Precancerous Conditions / diagnosis
  • Precancerous Conditions / pathology