A case of rheumatoid vasculitis with acquired reactive perforating collagenosis

Mod Rheumatol. 2019 May;29(3):547-550. doi: 10.1080/14397595.2016.1245175. Epub 2016 Nov 23.

Abstract

A 55-year-old man with rheumatoid arthritis (RA) presented hyperkeratotic erythematous papules with crusts or blisters on his limbs and buttocks. A histological study showed acquired reactive perforating collagenosis. Soon, skin lesions changed to umbilicated lesions with black necrosis, and the scar from his skin biopsy ulcerated with induration due to rheumatoid vasculitis. Systemic corticosteroids and tacrolimus administration resolved the RA and skin lesions. Rheumatoid vasculitis with acquired reactive perforating collagenosis has not been reported previously.

Keywords: Acquired reactive perforating collagenopsis; Rheumatoid arthritis; Rheumatoid vasculitis.

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Antirheumatic Agents / therapeutic use
  • Collagen Diseases / complications
  • Collagen Diseases / drug therapy
  • Collagen Diseases / pathology*
  • Humans
  • Male
  • Middle Aged
  • Rheumatoid Vasculitis / drug therapy
  • Rheumatoid Vasculitis / pathology*
  • Skin / pathology
  • Tacrolimus / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Antirheumatic Agents
  • Tacrolimus