Deep Brain Stimulation in Posttraumatic Tremor: A Series of Cases and Literature Review

Stereotact Funct Neurosurg. 2016;94(6):379-386. doi: 10.1159/000448078. Epub 2016 Nov 16.

Abstract

Background: Posttraumatic tremor (PTT) is the most frequent movement disorder secondary to cranioencephalic trauma and can be persistent and disabling.

Objectives: We review and assess the efficacy of deep brain stimulation (DBS) at the VIM/VOP/ZI (ventralis intermedius/ventrooralis posterior/zona incerta) complex level for the treatment of PTT.

Methods: During the period from 1999 to 2014, 5 patients diagnosed with PTT were selected who had experienced a major deterioration in their quality of life without improvement during medical treatment for more than 1 year. They underwent surgery for DBS at the VIM/VOP/ZI complex level, and the modified tremor scale before and after surgery was used for their follow-up.

Results: Each patient showed improvements in their symptoms after DBS compared with baseline, which was moderate (II) in 2 cases and marked (III) in the other cases. All of the improvements were maintained with chronic DBS, without tremor rebound.

Conclusions: Stimulation of the contralateral VIM/VOP/ZI complex resulted in a noticeable improvement in tremor and recovery of independence in basic daily activities in patients with PTT.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Brain Injuries, Traumatic / complications
  • Brain Injuries, Traumatic / diagnostic imaging
  • Brain Injuries, Traumatic / surgery*
  • Deep Brain Stimulation / methods*
  • Deep Brain Stimulation / trends
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Movement Disorders / diagnostic imaging
  • Movement Disorders / etiology
  • Movement Disorders / surgery*
  • Tremor / diagnostic imaging
  • Tremor / etiology
  • Tremor / surgery*
  • Young Adult