[Recipients adverse reactions in the Ibn Sina Hospital of Rabat: State 1999-2013]

Transfus Clin Biol. 2017 Feb;24(1):23-27. doi: 10.1016/j.tracli.2016.10.002. Epub 2016 Nov 11.
[Article in French]

Abstract

Purpose of study: The declaration of the recipients adverse reactions (RAR) is one of the field haemovigilance activities. It provides an evaluation of transfusion side effects and thus prevents their appearance. The aim of this study is to analyze, over 14 years, the RAR supports reported in Rabat Ibn Sina hospital.

Patients and methods: All of the RAR supports sending to the blood transfusion service were analyzed. The data collected from these supports are: clinical characteristics of the patient, type of incident observed and type of labile blood products (LBP) transfused.

Results: A total of 353 RAR were declared with a mean cumulative incidence of 1.7/1000 LBP delivered. Febrile non-hemolytic transfusion reactions represent 72.8% of the RAR declared. The RAR were classified as grade 1 in 87.1% of cases and were secondary to a transfusion of the red cell concentrates in 81.9%. ABO incompatibility was found in four cases (0.02/1000 LBP delivered).

Conclusion: The number of RAR reported by Rabat Ibn Sina hospital remains underestimated. Management and traceability RAR and rigorous investigation, under the responsibility of the corresponding haemovigilance contribute to the improvement of transfusion safety.

Keywords: Effets indésirables receveur; Labile blood products; Maroc; Morocco; Produits sanguins labiles; Recipients adverse reactions; Sécurité transfusionnelle; Transfusion safety.

MeSH terms

  • ABO Blood-Group System
  • Blood Group Incompatibility / epidemiology
  • Blood Safety*
  • Hospitals, Urban / statistics & numerical data
  • Humans
  • Incidence
  • Morocco / epidemiology
  • Transfusion Reaction / epidemiology*

Substances

  • ABO Blood-Group System