A weekly postpartum PGF protocol enhances uterine health in dairy cows

Reprod Biol. 2016 Dec;16(4):295-299. doi: 10.1016/j.repbio.2016.10.006. Epub 2016 Nov 7.

Abstract

Postpartum uterine health in dairy cows is crucial for the maintenance of good reproductive performance. In order to improve uterine health and reduce puerperal intrauterine infection, 608 Holstein cows received a weekly PGF protocol (3 i.m. injections of PGF at 7, 14 and 21 d postpartum). For comparison, 593 cows in the control group received injections of sterile saline at the same time. Uterine score at 14 d postpartum, the prevalence of endometritis at 21-27 d postpartum, and subsequent reproduction performance was evaluated. Cows in the treated group exhibited higher tonicity (P<0.05) of the uterus, with less prevalence of endometritis (10.4%, 63/608 vs. 34.6%, 205/593; P<0.001), and required shorter time to the first AI postpartum (67.5±3.4 d vs. 84.4±3.7 d, P<0.05) and to pregnancy (114.5±5.4 d vs. 131.4±5.8 d, P<0.05). In conclusion, the present study demonstrated that uterine health in Holstein cows can be promoted while puerperal infection can be suppressed by this weekly postpartum PGF protocol.

Keywords: Endometritis; Holstein cow; PGF(2α); Reproduction performance; Uterine health.

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases / diagnosis
  • Cattle Diseases / prevention & control*
  • Dinoprost / pharmacology*
  • Dinoprost / therapeutic use
  • Endometritis / diagnosis
  • Endometritis / prevention & control
  • Endometritis / veterinary*
  • Female
  • Postpartum Period*
  • Puerperal Infection / diagnosis
  • Puerperal Infection / prevention & control
  • Puerperal Infection / veterinary*
  • Uterus / drug effects*

Substances

  • Dinoprost