Synthesis and antibacterial activity of silver@carbon nanocomposites

J Inorg Biochem. 2017 Jan:166:64-67. doi: 10.1016/j.jinorgbio.2016.11.002. Epub 2016 Nov 5.

Abstract

In this work, hollow multiple-Ag-nanoclustes- C-shell nanocomposites (Ag@C) were synthesized by using silane coupling agent to graft carbon dots (CDs) with silver nanoparticles (AgNPs). CDs act as coating and stabilizing agent, protecting AgNPs from aggregation and oxidation. The resulting Ag@C nanocomposites demonstrate strong bactericidal effect against both gram-negative and gram-positive bacteria in the disk diffusion test. Cellular toxicity evaluation was performed using MTT assay. Meanwhile, the as-prepared Ag@C nanocomposites show a good biocompatibility.

Keywords: Antibacterial; Carbon dots; Nanocomposites; Silver@carbon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Bacterial Agents* / chemical synthesis
  • Anti-Bacterial Agents* / chemistry
  • Anti-Bacterial Agents* / pharmacology
  • CHO Cells
  • Carbon* / chemistry
  • Carbon* / pharmacology
  • Cricetinae
  • Cricetulus
  • Gram-Negative Anaerobic Bacteria / growth & development*
  • Gram-Positive Bacteria / growth & development*
  • Nanocomposites / chemistry*
  • Silver* / chemistry
  • Silver* / pharmacology

Substances

  • Anti-Bacterial Agents
  • Silver
  • Carbon