Pharmaceutical standardization of Kamsaharitaki granules

Ayu. 2015 Oct-Dec;36(4):416-420. doi: 10.4103/0974-8520.190698.

Abstract

Introduction: Kamsaharitaki Avaleha is a well-known ayurvedic preparation. Considering certain inconveniences of Avaleha, an attempt has been made to convert it into granules that are convenient in handling, dispensing, and storage.

Aim: To convert Kamsaharitaki Avaleha into granules form and develop standard manufacturing procedure.

Materials and methods: Seven pilot batches were prepared to fix the ratio of formulation composition. The procedure was repeated for 14 times to ensure the process validation.

Results: Converting into granules in presence of jaggery and Haritaki pulp is found to be difficult. Replacing these two with Khanda Sharkara and Haritaki powder yielded desired characteristics of granules.

Conclusion: This modified proportion of ingredients can be considered as standard in preparing Kamsaharitaki Avaleha granules. As no manufacturing and physicochemical properties are available for Kamsaharitaki granules; the current findings can be considered as standard for future studies.

Keywords: Granules; Kamsaharitaki Avaleha; Khanda Paka; standardization.