TERMA Framework for Biomedical Signal Analysis: An Economic-Inspired Approach

Biosensors (Basel). 2016 Nov 2;6(4):55. doi: 10.3390/bios6040055.

Abstract

Biomedical signals contain features that represent physiological events, and each of these events has peaks. The analysis of biomedical signals for monitoring or diagnosing diseases requires the detection of these peaks, making event detection a crucial step in biomedical signal processing. Many researchers have difficulty detecting these peaks to investigate, interpret and analyze their corresponding events. To date, there is no generic framework that captures these events in a robust, efficient and consistent manner. A new method referred to for the first time as two event-related moving averages ("TERMA") involves event-related moving averages and detects events in biomedical signals. The TERMA framework is flexible and universal and consists of six independent LEGO building bricks to achieve high accuracy detection of biomedical events. Results recommend that the window sizes for the two moving averages ( W 1 and W 2 ) have to follow the inequality ( 8 × W 1 ) ≥ W 2 ≥ ( 2 × W 1 ) . Moreover, TERMA is a simple yet efficient event detector that is suitable for wearable devices, point-of-care devices, fitness trackers and smart watches, compared to more complex machine learning solutions.

Keywords: crossover; eventogram transform; global health; internet-of-things devices; lagging indicator; mobile health; point-of-care devices; quasi-periodic signals; trend-following; wearable sensors.

MeSH terms

  • Algorithms
  • Datasets as Topic
  • Electrocardiography
  • Humans
  • Models, Theoretical
  • Point-of-Care Systems
  • Signal Processing, Computer-Assisted*