Homeostasis: How Neurons Achieve Temperature Invariance

Jan-Hendrik Schleimer; Susanne Schreiber

doi:10.1016/j.cub.2016.09.063

Homeostasis: How Neurons Achieve Temperature Invariance

Curr Biol. 2016 Nov 7;26(21):R1141-R1143. doi: 10.1016/j.cub.2016.09.063.

Authors

Jan-Hendrik Schleimer¹, Susanne Schreiber²

Affiliations

¹ Institute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, 10115 Berlin, Germany; Bernstein Center for Computational Neuroscience Berlin, 10115 Berlin, Germany.
² Institute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, 10115 Berlin, Germany; Bernstein Center for Computational Neuroscience Berlin, 10115 Berlin, Germany. Electronic address: s.schreiber@hu-berlin.de.

PMID: 27825449
DOI: 10.1016/j.cub.2016.09.063

Abstract

Temperature influences physiological processes and can corrupt nervous system function. A modelling study shows how regulation of ion channel expression can establish an acute temperature invariance of neuronal responses despite temperature-dependent and variable ionic conductances.

Publication types

Comment

MeSH terms

Homeostasis
Ion Channels*
Nervous System Physiological Phenomena*
Neurons
Temperature

Substances

Ion Channels