The Relation of White-on-White Standard Automated Perimetry, Short Wavelength Perimetry, and Optic Coherence Tomography Parameters in Ocular Hypertension

J Glaucoma. 2016 Dec;25(12):939-945. doi: 10.1097/IJG.0000000000000446.

Abstract

Purpose: The purpose of this study is to examine the demographics, clinical properties, and the relation between white-on-white standard automated perimetry (SAP), short wavelength automated perimetry (SWAP), and optical coherence tomographic (OCT) parameters of patients with ocular hypertension.

Materials and methods: Sixty-one eyes of 61 patients diagnosed with ocular hypertension in the Ankara Numune Education and Research Hospital ophthalmology unit between January 2010 and January 2011 were included in this study. All patients underwent SAP and SWAP tests with the Humphrey visual field analyser using the 30.2 full-threshold test. Retinal nerve fiber layers (RNFL) and optic nerve heads of patients were evaluated with Stratus OCT.

Results: Positive correlation was detected between SAP pattern standard deviation value and average intraocular pressure (P=0.017), maximum intraocular pressure (P=0.009), and vertical cup to disc (C/D) ratio (P=0.009). Positive correlation between SWAP median deviation value with inferior (P=0.032), nasal (P=0.005), 6 o'clock quadrant RNFL thickness (P=0.028), and Imax/Tavg ratio (P=0.023) and negative correlation with Smax/Navg ratio (P=0.005) were detected. There was no correlation between central corneal thickness and peripapillary RNFL thicknesses (P>0.05).

Conclusions: There was no relation between SAP median deviation, pattern standard deviation values and RNFL thicknesses and optic disc parameters of the OCT. By contrast significant correlation between several SWAP parameters and OCT parameters were detected. SWAP appeared to outperform achromatic SAP when the same 30-2 method was used.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Intraocular Pressure*
  • Male
  • Middle Aged
  • Nerve Fibers / pathology
  • Ocular Hypertension / diagnosis*
  • Ocular Hypertension / physiopathology
  • Optic Disk / pathology
  • Retinal Ganglion Cells / pathology*
  • Tomography, Optical Coherence / methods*
  • Tonometry, Ocular
  • Visual Field Tests / methods*
  • Visual Fields / physiology*