Uranium Workers Demonstrate Lower Lobe Predominant Irregular Pneumoconiotic Opacities on Chest Radiographs

J Health Care Poor Underserved. 2016;27(4A):116-127. doi: 10.1353/hpu.2016.0193.

Abstract

Background: There is a paucity of literature on the chest radiographic findings in uranium workers.

Objective: To characterize the chest radiographic findings of pneumoconiosis in a New Mexican cohort of uranium workers.

Methods: The most recent results from chest radiographs were abstracted in this cross-sectional study.

Results: Radiographs showed small pneumoconiotic opacities of profusion score of ≥ 1/0 in 155/429 (36.1%) uranium workers. The most common shape/size of the primary and secondary opacities was s (90.3%) and t (83.7%) types, respectively. Lower lung zones were the most affected. American Indians were the population group at greatest odds for having profusion score ≥ 1/0 (O.R. 2.65, 95% C.I. 1.61, 4.36).

Conclusions: Uranium workers' pneumoconiosis is associated with predominantly lower lobe, irregular, and small opacities. Clinical providers and policymakers must consider uranium workers' pneumoconiosis in the differential diagnosis for lower lobe-predominant interstitial lung disease, in the appropriate exposure setting.

MeSH terms

  • Cross-Sectional Studies
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology*
  • Occupational Exposure*
  • Pneumoconiosis / diagnostic imaging*
  • Radiography
  • Uranium / toxicity*

Substances

  • Uranium