A retrospective study detects a novel variant of porcine epidemic diarrhea virus in England in archived material from the year 2000

Falko Steinbach; Akbar Dastjerdi; Julie Peake; S Anna La Rocca; Frank P Tobin; Jean-Pierre Frossard; Susanna Williamson

doi:10.7717/peerj.2564

A retrospective study detects a novel variant of porcine epidemic diarrhea virus in England in archived material from the year 2000

PeerJ. 2016 Oct 27:4:e2564. doi: 10.7717/peerj.2564. eCollection 2016.

Authors

Falko Steinbach¹, Akbar Dastjerdi¹, Julie Peake¹, S Anna La Rocca¹, Frank P Tobin², Jean-Pierre Frossard¹, Susanna Williamson³

Affiliations

¹ Department of Virology, Animal and Plant Health Agency , Addlestone , Surrey , United Kingdom.
² Holmefield Farm Services Ltd , Murton , Yorkshire , United Kingdom.
³ Surveillance Intelligence Unit, Animal and Plant Health Agency , Bury St Edmunds , Suffolk , United Kingdom.

Abstract

Outbreaks of porcine epidemic diarrhea (PED) were first recorded in England in the 1970s and continued to be confirmed until 2002. Retrospective analysis of archived material from one of the last confirmed cases in England in the year 2000 demonstrates the previous existence of a very diverse PED virus strain. Following the outbreaks of PED in North America in 2013, there has been renewed interest in phylogenetic analysis of sequences from PEDV strains worldwide. There is a gap in the available sequence data between the mid 1980s and the mid 2000s. This work is an example of how this gap can be at least partially filled by the examination of archived material.

Keywords: Diarrhea; England; PEDV; Phylogeny; Pig; Variant.

Grants and funding

Defra project “Scanning surveillance for Pig Diseases in England and Wales” (ED1200) funded laboratory and staff costs of this work. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.