Fournier Gangrene Caused by Candida albicans in an Infant After Cardiac Surgery

Mycopathologia. 2017 Apr;182(3-4):409-412. doi: 10.1007/s11046-016-0086-4. Epub 2016 Nov 2.

Abstract

Fournier gangrene is a rare, rapidly progressive, life-threatening condition. We report a 23-day-old boy with pulmonary atresia and ventricular septal defect treated surgically, who developed Fournier gangrene. Emergency surgery was performed with tissue sampling for microbiological examination. Candida albicans was confirmed; caspofungin followed by fluconazole was administered with excellent results.

Keywords: Candida albicans infection; Congenital heart defects; Echinocandins; Fluconazole; Fournier gangrene; Pediatric cardiac surgery.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candida albicans / isolation & purification*
  • Candidiasis, Cutaneous / diagnosis*
  • Candidiasis, Cutaneous / drug therapy
  • Candidiasis, Cutaneous / microbiology
  • Candidiasis, Cutaneous / pathology*
  • Caspofungin
  • Echinocandins / therapeutic use
  • Fluconazole / therapeutic use
  • Fournier Gangrene / drug therapy
  • Fournier Gangrene / etiology*
  • Fournier Gangrene / pathology*
  • Humans
  • Infant, Newborn
  • Lipopeptides / therapeutic use
  • Male
  • Scrotum / microbiology
  • Scrotum / pathology*
  • Thoracic Surgery
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Echinocandins
  • Lipopeptides
  • Fluconazole
  • Caspofungin