Abstract
Fournier gangrene is a rare, rapidly progressive, life-threatening condition. We report a 23-day-old boy with pulmonary atresia and ventricular septal defect treated surgically, who developed Fournier gangrene. Emergency surgery was performed with tissue sampling for microbiological examination. Candida albicans was confirmed; caspofungin followed by fluconazole was administered with excellent results.
Keywords:
Candida albicans infection; Congenital heart defects; Echinocandins; Fluconazole; Fournier gangrene; Pediatric cardiac surgery.
MeSH terms
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Antifungal Agents / therapeutic use
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Candida albicans / isolation & purification*
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Candidiasis, Cutaneous / diagnosis*
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Candidiasis, Cutaneous / drug therapy
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Candidiasis, Cutaneous / microbiology
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Candidiasis, Cutaneous / pathology*
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Caspofungin
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Echinocandins / therapeutic use
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Fluconazole / therapeutic use
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Fournier Gangrene / drug therapy
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Fournier Gangrene / etiology*
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Fournier Gangrene / pathology*
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Humans
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Infant, Newborn
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Lipopeptides / therapeutic use
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Male
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Scrotum / microbiology
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Scrotum / pathology*
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Thoracic Surgery
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Treatment Outcome
Substances
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Antifungal Agents
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Echinocandins
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Lipopeptides
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Fluconazole
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Caspofungin