Deterioration of pulmonary hypertension and pleural effusion with bosutinib following dasatinib lung toxicity

Marianne Riou; Andrei Seferian; Laurent Savale; Marie-Camille Chaumais; Christophe Guignabert; Matthieu Canuet; Pascal Magro; Delphine Rea; Olivier Sitbon; Xavier Jaïs; Marc Humbert; David Montani

doi:10.1183/13993003.01410-2016

Deterioration of pulmonary hypertension and pleural effusion with bosutinib following dasatinib lung toxicity

Eur Respir J. 2016 Nov;48(5):1517-1519. doi: 10.1183/13993003.01410-2016. Epub 2016 Oct 6.

Authors

Marianne Riou^{1

2

3

4}, Andrei Seferian^{1

2

3}, Laurent Savale^{1

2

3}, Marie-Camille Chaumais^{1

3

5}, Christophe Guignabert^{1

3}, Matthieu Canuet⁴, Pascal Magro⁶, Delphine Rea⁷, Olivier Sitbon^{1

2

3}, Xavier Jaïs^{1

2

3}, Marc Humbert^{1

2

3}, David Montani^{8

2

3}

Affiliations

¹ Université Paris-Sud and Université Paris-Saclay, Le Kremlin-Bicêtre, France.
² AP-HP, Service de Pneumologie, Centre de Référence de l'Hypertension Pulmonaire Sévère, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
³ INSERM UMR_S 999, Le Plessis Robinson, France.
⁴ Service de Pneumologie, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
⁵ AP-HP, Service de Pharmacie, DHU Thorax Innovation, Hôpital Antoine Béclère, Clamart, France.
⁶ Service de Pneumologie, CHRU de Tours, Tours, France.
⁷ AP-HP, Service d'Hématologie Adulte, Hôpital Saint-Louis, Paris, France.
⁸ Université Paris-Sud and Université Paris-Saclay, Le Kremlin-Bicêtre, France david.montani@aphp.fr.

PMID: 27799395
DOI: 10.1183/13993003.01410-2016

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Aniline Compounds / adverse effects*
Dasatinib / adverse effects*
Female
Humans
Hypertension, Pulmonary / chemically induced*
Lung / pathology
Middle Aged
Nitriles / adverse effects*
Pleural Effusion / chemically induced*
Protein Kinase Inhibitors / adverse effects*
Quinolines / adverse effects*

Substances

Aniline Compounds
Nitriles
Protein Kinase Inhibitors
Quinolines
bosutinib
Dasatinib