A new tetrahydrobenzofuranone metabolite from Streptomyces sp. HS-NF-853

Nat Prod Res. 2017 Apr;31(8):878-882. doi: 10.1080/14786419.2016.1250091. Epub 2016 Oct 31.

Abstract

A new tetrahydrobenzofuranone derivative, strefuranone A (1), was isolated from Streptomyces sp. HS-NF-853. The structure of the compound was elucidated on the basis of MS and extensive NMR analysis.

Keywords: Tetrahydrobenzofuranone; actinomycetes; strefuranone A; structure elucidation.

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / isolation & purification
  • Antineoplastic Agents / pharmacology
  • Benzofurans / chemistry
  • Benzofurans / isolation & purification*
  • Benzofurans / metabolism
  • Benzofurans / pharmacology
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Fermentation
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Streptomyces / chemistry
  • Streptomyces / metabolism*

Substances

  • Antineoplastic Agents
  • Benzofurans
  • strefuranone A