Abstract
Lysine deacetylases act on many other proteins apart from histones, with effects on metabolism and gene expression. We need to be cautious that therapeutically used KDACi have a much more widespread impact than anticipated.
MeSH terms
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Acetylation
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Epigenesis, Genetic
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Histone Deacetylase Inhibitors / therapeutic use*
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Histone Deacetylases / metabolism*
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Humans
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Lysine / metabolism*
Substances
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Histone Deacetylase Inhibitors
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Histone Deacetylases
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Lysine