gsrc: an R package for genome structure rearrangement calling

Bioinformatics. 2017 Feb 15;33(4):545-546. doi: 10.1093/bioinformatics/btw648.

Abstract

Summary: Genome structure rearrangements are a common phenomenon in allopolyploid species. Deletions, duplications and homeologous non-reciprocal translocations (HNRT) between the highly similar subgenomes can be observed, which are known to have a large impact on phenotypic traits. Current research is limited because these rearrangements can be located genome wide only by cost intensive sequencing approaches and not reliably in high-density array genotyping data. We developed gsrc, an R-package to detect genome structure rearrangements from genotyping data in allopolyploid species including exchanges between subgenomes. We exemplarily apply gsrc to a publicly available Brassica napus dataset.

Availability and implementation: The compiled R-package and source code are available at http://cran.r-project.org/web/packages/gsrc/ .

Contact: birgit.samans@uni-giessen.de.

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Brassica napus / genetics
  • Genome, Plant*
  • Genomics / methods*
  • Polyploidy*
  • Sequence Analysis, DNA / methods*
  • Software*