Therapeutic laryngoscopy during exercise: A novel non-surgical therapy for refractory EILO

Pediatr Pulmonol. 2017 Jun;52(6):813-819. doi: 10.1002/ppul.23634. Epub 2016 Oct 31.

Abstract

Background: Exercise-induced laryngeal obstruction (EILO) may affect as many as 6% of the adolescent population, with some patients experiencing symptoms refractory to conservative interventions.

Objectives: This report describes therapeutic laryngoscopy during exercise, a novel, non-surgical intervention that harnesses real-time laryngoscopy video as biofeedback to control laryngeal aperture during high-intensity exercise. Additionally, we quantitate patient-reported perceptions of procedure safety, tolerability, learning value, and effectiveness.

Methods: Clinical EILO patients with symptoms refractory to conventional respiratory retraining and other therapies were referred for the procedure which features laryngoscopy video as biofeedback during serial physician-guided 1-min exercise sprints. We quantify perceptions of procedure safety, tolerability, learning value, and effectiveness through questionnaires offered to all patients as well as observers of the procedure.

Results: Forty-one patients and 37 parent observers were approached for feedback; 88% of patients and 95% of observers consented to participation. Patients and observers reported perceptions of safety and tolerability (81% and 86%, respectively), learning value (78% and 91%, respectively), and effectiveness (58% and 80%, respectively) with patient age predicting some responses. Seventy-five percent of patients noted that "Since the procedure, my breathing during exercise has improved," and 85% of this group noted that therapeutic laryngoscopy during exercise was "the most important therapy leading to my breathing improvement." The procedure also provided insight into the psychological experience of patients, a domain not clinically apparent prior to the procedure.

Conclusions: Our data support further study of therapeutic laryngoscopy during exercise as a possible intervention for patients with refractory EILO. Pediatr Pulmonol. 2017;52:813-819. © 2016 Wiley Periodicals, Inc.

Keywords: continuous laryngoscopy during exercise; exercise-induced laryngeal obstruction; exertional dyspnea; therapeutic laryngoscopy during exercise; vocal cord dysfunction.

MeSH terms

  • Adolescent
  • Adult
  • Airway Obstruction / diagnostic imaging*
  • Airway Obstruction / therapy*
  • Exercise*
  • Female
  • Humans
  • Laryngeal Diseases / diagnostic imaging*
  • Laryngeal Diseases / therapy*
  • Laryngoscopy / methods*
  • Larynx / diagnostic imaging
  • Male
  • Respiration
  • Surveys and Questionnaires
  • Young Adult