Telocytes in Exocrine Glands Stroma

Adv Exp Med Biol. 2016:913:163-176. doi: 10.1007/978-981-10-1061-3_11.

Abstract

Stroma is viewed as the supportive framework of a predominant epithelial organ, comprising mostly of connective tissue, blood vessels and nerves. Since the discovery of telocytes one decade ago (Popescu and Faussone-Pellegrini J Cell Mol Med 2010;14(4):729-40), their presence was proven in several exocrine gland stromata, including major and minor salivary glands, mammary glands as well as exocrine pancreas.Telocytes have been found in a close connection with acinar and ductal structures but also with their stromal neighbours - nerves, blood vessels or other connective elements, either cells or collagen fibres.The approaches used to reveal the telocytes' location were immunohistochemistry and electron microscopy.

Keywords: Mammary gland; Pancreas; Parotid; Submandibular; Telocytes.

Publication types

  • Review

MeSH terms

  • Acinar Cells / metabolism
  • Acinar Cells / ultrastructure
  • Animals
  • Blood Vessels / metabolism
  • Blood Vessels / ultrastructure
  • Connective Tissue / metabolism
  • Connective Tissue / ultrastructure
  • Humans
  • Immunohistochemistry
  • Mammary Glands, Human / metabolism
  • Mammary Glands, Human / ultrastructure*
  • Microscopy, Electron
  • Pancreas, Exocrine / metabolism
  • Pancreas, Exocrine / ultrastructure*
  • Rats
  • Salivary Glands / metabolism
  • Salivary Glands / ultrastructure*
  • Telocytes / metabolism
  • Telocytes / ultrastructure*