Complete Genome Sequence of Pigmentation-Negative Yersinia pestis Strain Cadman

Sean Lovett; Kitty Chase; Galina Koroleva; Gustavo Palacios; David Rozak; Jason T Ladner

doi:10.1128/genomeA.01207-16

Complete Genome Sequence of Pigmentation-Negative Yersinia pestis Strain Cadman

Genome Announc. 2016 Oct 27;4(5):e01207-16. doi: 10.1128/genomeA.01207-16.

Authors

Sean Lovett¹, Kitty Chase², Galina Koroleva¹, Gustavo Palacios¹, David Rozak³, Jason T Ladner¹

Affiliations

¹ Center for Genome Sciences, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
² Diagnostic Systems Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
³ Diagnostic Systems Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA david.a.rozak2.ctr@mail.mil.

Abstract

Here, we report the genome sequence of Yersinia pestis strain Cadman, an attenuated strain lacking the pgm locus. Y. pestis is the causative agent of plague and generally must be worked with under biosafety level 3 (BSL-3) conditions. However, strains lacking the pgm locus are considered safe to work with under BSL-2 conditions.

Grants and funding

This work was supported by the Defense Threat Reduction Agency, project CB10219. Opinions, interpretations, conclusions, and recommendations are those of the authors and do not necessarily reflect the official policy or position of the U.S. Army, the U.S. Department of Defense, or the U.S. government.