Two new prenylated flavonoids from the roots of Berberis thunbergii DC

Nusrat Hussain; Achyut Adhikari; Malik Shoaib Ahmad; Atia-Tul- Wahab; Meher Ali; M Iqbal Choudhary

doi:10.1080/14786419.2016.1244195

Two new prenylated flavonoids from the roots of Berberis thunbergii DC

Nat Prod Res. 2017 Apr;31(7):785-790. doi: 10.1080/14786419.2016.1244195. Epub 2016 Oct 27.

Authors

Nusrat Hussain¹, Achyut Adhikari¹, Malik Shoaib Ahmad¹, Atia-Tul- Wahab², Meher Ali¹, M Iqbal Choudhary^{1

2

3}

Affiliations

¹ a H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences , University of Karachi , Karachi , Pakistan.
² b Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences , University of Karachi , Karachi , Pakistan.
³ c Faculty of Science, Department of Biochemistry , King Abdulaziz University , Jeddah , Saudi Arabia.

PMID: 27788592
DOI: 10.1080/14786419.2016.1244195

Abstract

Two new prenylated flavonoids, thunbergiols A (1) and B (2), along with three known compounds, chrysin (3), quercetin (4) and berberine (5) were obtained from the methanolic extract of roots of Berberis thunbergii DC. MS, NMR and other spectroscopic techniques were employed for their structural characterisation.

Keywords: Berberis thunbergii DC.; berberine; prenylated flavonoids; thunbergiol A; thunbergiol B.

MeSH terms

Berberine / chemistry
Berberine / isolation & purification
Berberis / chemistry*
Flavonoids / chemistry*
Flavonoids / isolation & purification
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Extracts / chemistry
Plant Roots / chemistry
Prenylation
Quercetin / chemistry
Quercetin / isolation & purification

Substances

Flavonoids
Plant Extracts
thunbergiol A
thunbergiol B
Berberine
chrysin
Quercetin