Koninginins R-S from the endophytic fungus Trichoderma koningiopsis

Ming Hu; Qi-Ling Li; Ya-Bin Yang; Kai Liu; Cui-Ping Miao; Li-Xing Zhao; Zhong-Tao Ding

doi:10.1080/14786419.2016.1250086

Koninginins R-S from the endophytic fungus Trichoderma koningiopsis

Nat Prod Res. 2017 Apr;31(7):835-839. doi: 10.1080/14786419.2016.1250086. Epub 2016 Oct 26.

Authors

Ming Hu¹, Qi-Ling Li¹, Ya-Bin Yang¹, Kai Liu², Cui-Ping Miao², Li-Xing Zhao², Zhong-Tao Ding¹

Affiliations

¹ b School of Chemical Science and Technology , Yunnan University , Kunming , People's Republic of China.
² a Yunnan Institute of Microbiology, School of Life Science , Yunnan University , Kunming , People's Republic of China.

PMID: 27784167
DOI: 10.1080/14786419.2016.1250086

Abstract

Two new metabolites named koninginins R-S (1-2) were isolated from the culture of Trichoderma koningiopsis YIM PH30002. Their chemical structures were elucidated by the extensive spectroscopic analysis. These isolated compounds showed certain antifungal activities against phytopathogens, Fusarium flocciferum and Fusarium oxysporum.

Keywords: Trichoderma koningiopsis; antifungal activity; koninginin.

MeSH terms

Antifungal Agents / chemistry*
Antifungal Agents / pharmacology*
Benzofurans / chemistry*
Benzofurans / pharmacology*
Benzopyrans / chemistry*
Benzopyrans / pharmacology*
Fermentation
Fusarium / drug effects
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Spectrophotometry, Ultraviolet
Trichoderma / chemistry*

Substances

7-O-methylkoninginin D
Antifungal Agents
Benzofurans
Benzopyrans
koninginin R
koninginin S