Intensity of Oxidative Stress in Mongoloid and Caucasian Patients with Type 1 Diabetes Mellitus

Bull Exp Biol Med. 2016 Oct;161(6):767-769. doi: 10.1007/s10517-016-3505-0. Epub 2016 Oct 26.

Abstract

Specific features of LPO were studied in Mongoloid and Caucasian patients with type 1 diabetes mellitus. The intensity of LPO in Mongoloid patients was lower than in Caucasians: the level of primary and intermediate products was by lower 1.53 and 1.83 times, while total antioxidant activity was elevated by 1.44 times, which was also supported by oxidative stress coefficient (1.35 in Mongoloids and 2.32 in Caucasians). These differences suggest that differentiated approach is required for the treatment of these patients.

Keywords: oxidative stress; race; type 1 diabetes mellitus.

MeSH terms

  • Adult
  • Antioxidants / metabolism*
  • Asian People
  • Diabetes Mellitus, Type 1 / blood*
  • Diabetes Mellitus, Type 1 / diagnosis
  • Diabetes Mellitus, Type 1 / ethnology*
  • Diabetes Mellitus, Type 1 / physiopathology
  • Female
  • Glutathione Disulfide / blood
  • Humans
  • Lipid Peroxidation
  • Male
  • Oxidative Stress*
  • Russia
  • Superoxide Dismutase / blood
  • Thiobarbituric Acid Reactive Substances / metabolism
  • Vitamin A / blood
  • White People
  • alpha-Tocopherol / blood

Substances

  • Antioxidants
  • Thiobarbituric Acid Reactive Substances
  • Vitamin A
  • Superoxide Dismutase
  • alpha-Tocopherol
  • Glutathione Disulfide