Bioactive Natural Products from Animal Associated-Microbes

Mini Rev Med Chem. 2017;17(17):1588-1601. doi: 10.2174/1389557516666161024144014.

Abstract

Objective: Animal associated-microbes are miroorganisms living inside animal hosts during some parts of their life. In view of the special environment, it is considered that the unique microbes might be the producer of new compounds with diversity biological activities.

Conclusion: This review summarizes new findings (mainly described since 2011) concerning the characteristics of various natural products that can be extracted from animal associated-microbes, highlighting that animal related microorganisms represent an underexplored reservoir for the discovery of molecules with unique scaffolds and promising biological activities.

Keywords: Alkaloids; animal associated-microbes; bioactivity; hybrids; natural products; peptides; polyketides; terpenoids.

Publication types

  • Review

MeSH terms

  • Animals
  • Bacteria / chemistry*
  • Bacteria / metabolism
  • Biological Products / chemistry
  • Biological Products / isolation & purification
  • Biological Products / metabolism*
  • Fungi / chemistry*
  • Fungi / metabolism

Substances

  • Biological Products